What You Can Expect With BreathTek® UBT for H. pylori

BreathTek UBT can be administered in your doctor’s office or in one of the many national and regional labs, like Quest Diagnostics® and LabCorp®, located across the country. Before you take the test, follow the few simple steps listed below to make sure that your results are as accurate as possible. If you are already prepared before your appointment, you may be able to take the test immediately.

Preparing to take BreathTek UBT

For the best test results:
  • Do not eat or drink for 1 hour prior to taking the test.
  • Do not take any of the following medications for 2 weeks prior to the test:
    • All antibiotics
    • Proton pump inhibitors (PPIs) or their generic versions such as Aciphex® (rabeprazole), Nexium® (esomeprazole), Prevacid® (lansoprazole), Prilosec® (omeprazole), Prilosec OTC® (omeprazole), Protonix® (pantoprazole), Zegerid® (omeprazole/sodium bicarbonate), and Dexilant® (dexlansoprazole)
    • Bismuth preparations such as Pepto Bismol®
H. pylori

If you are currently taking a PPI:

  • It is still recommended that antibiotics, PPIs, or bismuth medications not be taken within 2 weeks prior to taking the BreathTek UBT.
  • If you are taking a PPI and test positive for H. pylori infection, the result is considered positive and eradication therapy can be started immediately. If the test is negative, it may be a false negative and results should be confirmed with a second breath test 2 weeks after discontinuing the PPI.
  • Histamine blockers (H2 antagonists) may be substituted for PPIs. These medications include Zantac® (ranitidine), Tagamet® (cimetidine), Pepcid® (famotidine), and Axid® (nizatidine). The effect of histamine blockers may reduce urease activity on urea breath tests. Histamine blockers may be discontinued for 24-48 hours before the BreathTek UBT.1

If you are taking antacids:

  • You may continue taking antacids prior to testing. The use of antacids does not appear to affect the accuracy of the BreathTek UBT.

When testing to confirm that you’re cured:

  • The test should be administered at least 4 weeks after completion of treatment. The conditions above also apply.

4 Simple Steps to Rule Out an H. pylori Infection

During the test, a health care professional will ask you to perform a few simple steps:

exhale into blue collection bag

Step 1

You will inhale, hold your breath momentarily, and then exhale into a blue collection bag.

drink the solution

Step 2

After the HCP mixes the Pranactin®-Citric drug solution with water, you will drink the solution through a straw from the plastic cup provided.

wait 15 minutes

Step 3

Wait 15 minutes.

exhale into pink collection bag

Step 4

Once again you will inhale, hold your breath momentarily, and then exhale into a pink collection bag.

Be confident that your treatment worked.

If you test positive for an H. pylori infection, your doctor may prescribe a course of antibiotics to treat it. H. pylori can be a difficult infection to kill, and the bacteria may survive treatment.2 Ask your doctor if you need to take the BreathTek UBT again after you’ve finished the course of antibiotics to make sure that the infection is cured.

Note: Registered Marks are the property of their respective owners.

Chey WD, Wong BCY; Practice Parameters Committee of the American College of Gastroenterology. American College of Gastroenterology guideline on the management of Helicobacter pylori infection. Am J Gastroenterol. 2007;102(8):1808-1825. http://s3.gi.org/physicians/guidelines/ManagementofHpylori.pdf. Accessed Oct 10, 2014.
Ables AZ, Simin I, Melton ER. Update on Helicobacter pylori treatment. Am Fam Physician. 2007;75(3):351-358. http://www.aafp.org/afp/2007/0201/p351.html. Accessed Oct 10, 2014.

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Curious About the Test?

Learn how BreathTek UBT is administered in this instructional video.

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Learn about BreathTek UBT and how to prepare for the test.

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