Features of BreathTek<sup>®</sup> UBT for <span class="hpylori-bold">H. pylori</span>

BreathTek UBT is:

  • Convenient — Can be done in your doctor’s office or at a lab
  • Easy — Simple to do, no invasive procedures, no messy collection cups, no painful needles
  • Fast — The entire test process takes about 20 minutes
  • Covered — Most national and regional health plans cover BreathTek UBT

There are other testing options available to diagnose and confirm the cure of an H. pylori infection. Urea breath tests and stool tests both diagnose active infections in the stomach, while a blood test can only identify antibodies that could be from an active or previous infection. The 2 charts below highlight the differences between each test’s ability to accurately diagnose an infection.

Testing options for diagnosing an H. pylori infection in adults

  Test Sensitivity* Specificity
  BreathTek UBT 95% 90%
  Stool test 93% 93%
  Blood test 85% 79%
  Endoscopy / biopsy 93% 90%

Testing options for confirming the cure of an H. pylori infection in adults

  Test Sensitivity* Specificity
  BreathTek UBT 96% 96%
  Stool test 89% 89%
  Blood test ———NOT RECOMMENDED1———
  Endoscopy / biopsy 93% 90%

*Sensitivity refers to the percentage of people with the infection who get a positive result.
Specificity refers to the percentage of people without the infection who get a negative result.

Note: The percentages in these tables are weighted mean values and not the result of a comparative study.
Note: The recent use of PPIs, bismuth, or antibiotics can reduce the sensitivity of UBT and stool tests.

Inaccurate results may be caused by drugs you are taking within 2 weeks prior to this test. These may include:
  • Proton pump inhibitors (PPIs) such as Aciphex® (rabeprazole), Nexium® (esomeprazole), Prevacid® (lansoprazole), Prilosec® (omeprazole), Prilosec OTC® (omeprazole), Protonix® (pantoprazole), Zegerid® (omeprazole/sodium bicarbonate), and Dexilant® (dexlansoprazole)
  • Antibiotics
  • Bismuth-based drugs (Pepto-Bismol®)
Consider all false negative and false positive factors, including :
  • Urease associated with other gastric spiral organisms observed in humans (Section 4.5 of the Package Insert.)
Inaccurate test results can also occur if:
  • The second breath sample is collected too soon.
  • You were treated for H. pylori with antibiotics, but take your confirmation test with BreathTek UBT less than 4 weeks after completing your therapy.
  • The straw provided in the kit is not used.
If you are taking antacids:
  • You may continue taking antacids prior to testing. The use of antacids does not appear to affect the accuracy of the BreathTek UBT.

Note: Registered Marks are the property of their respective owners.

Could your child be suffering from an H. pylori infection?

Home video

Learn how BreathTek UBT is administered in this instructional video.

Learn about BreathTek UBT and how to prepare for the test.

References
  • Chey WD, Wong BCY; Practice Parameters Committee of the American College of Gastroenterology. American College of Gastroenterology guideline on the management of Helicobacter pylori infection. Am J Gastroenterol. 2007;102(8):1808-1825. http://s3.gi.org/physicians/guidelines/ManagementofHpylori.pdf. Accessed August 21, 2017.