Confirming eradication accurately is more important than ever

American College of Gastroenterology (ACG) reports declining H. pylori eradication rates1

  • Evidence shows that eradication therapy can fail in 1 out of 4 patients2
    • Patients may not complete full eradication treatment regimen2
    • Incidence of antibiotic resistance is escalating2
Read the ACG Guideline at the Resource Page here

H. pylori is associated with significant morbidity3,4

  • Causes more than 90% of duodenal ulcers and up to 80% of gastric ulcers3
  • Linked to 60% of gastric cancer (adenocarcinoma and primary ß-cell lymphoma [MALT lymphoma]) cases4
    • The World Health Organization has classified H. pylori as a Group 1 carcinogen5

ACG recommends testing to confirm H. pylori eradication1

  • Testing is recommended  for all patients treated for H. pylori-associated ulcer,
    H. pylori-associated MALT lymphoma, or resected early gastric cancer1
  • Patients want to know if their infection has been treated successfully2

Urea Breath Test (UBT) method: ACG-recommended test to confirm eradication1

  • By assessing the entire gastric mucosa, BreathTek UBT avoids the sampling errors seen in biopsy methods6
  • Serologic testing for H. pylori is not recommended by the American Gastroenterological Association (AGA) and should not be used to confirm eradication7

About one third of the US population may be infected with H. pylori8

  • Prevalence tends to increase with age, reaching 20% to 50% of adults in Europe and North America
  • High H. pylori rates are predominantly associated with low socioeconomic status
  • High intrafamilial rates of infection and reinfection indicate person-to-person transmission as the primary method of transmission
  • After eradication, reinfection rates in adults can be as high as 24% in low-income communities

Readily and Widely Available

Can be performed in the office or at a lab

Along the US/Mexico border, H. pylori incidence rates of >80% have been reported in adults aged 30 to 69 years8 The performance characteristics for persons under the age of 18 have not been established for BreathTek UBT.