BreathTek® UBT for H. pylori
may be administered to
patients currently taking PPIs
- It is still recommended that antimicrobials, PPIs, or bismuth preparations not be taken within 2 weeks prior to administering the BreathTek UBT1
- If patients currently taking PPIs test positive for H. pylori, it is considered positive and eradication therapy can be started immediately1; if the test is negative, it may be a false negative and results should be confirmed with a second breath test 2 weeks after discontinuing PPIs1
Confirming H. pylori eradication
accurately is more important
American College of Gastroenterology reports declining eradication rates1
- Evidence shows that eradication therapy can fail in 1 out of 4 patients2
BreathTek UBT for H. pylori has excellent sensitivity (95.5%)
and specificity (96.0%) when confirming eradication1
Sensitivity and Specificity of post-treatment tests for H. pylori infection2,3
* Data are weighted mean values. Compilation of data is not the result of a comparative study.
ELISA = enzyme-linked immunosorbent assay.
† Serology is not effective in post-treatment testing because it cannot distinguish between active and passive infection.
False negative test results may be caused by
- Ingestion of antimicrobials, proton pump inhibitors, and bismuth preparations within 2 weeks prior to administering BreathTek UBT
- Premature POST-DOSE breath collection time for a patient with a marginally positive BreathTek UBT result
- Post-treatment assessment with the BreathTek UBT less than 4 weeks after completion of treatment for the eradication of H. pylori
A false positive test may occur due to urease associated with other gastric spiral organisms observed in humans, such as Helicobacter heilmannii and Achlorhydria.
BreathTek UBT makes H. pylori detection convenient
SIMPLE, QUICK ADMINISTRATION IN YOUR OFFICE OR AT A LAB
STEP 1: Collect baseline breath sample
- Patient breathes into an easy-to-inflate collection bag
STEP 2: Have patient drink Pranactin®-Citric drug solution
- Just empty contents of drug pouch into the drinking cup and add drinking water to the fill line
STEP 3: Patient waits 15 minutes
STEP 4: Collect second breath sample
- Send samples to a local lab or perform the analysis in your office
- Specific instruments are available so both administration and analysis can be performed in-office
- The UBT method is the first-choice noninvasive test because of its high accuracy, convenience, and availability2
- By simply measuring the ratio of 13CO2 to 12CO2 in the patient's breath samples, BreathTek UBT accurately detects H. pylori-associated urease (95.5% sensitivity and 96.0% specificity to confirm eradication)1,2
*Not based on a direct-comparison study between BreathTek UBT and other H. pylori tests.
BreathTek UBT contains phenylalanine, a component of aspartame; use with caution in diabetic or PKU patients
BreathTek UBT is Simple to UseExperience the Simplicity